Scientific Program

 

Monday – August 24th, 2015

5:30 to 6:00 pm Opening Ceremony
6:00 to 7:00 pm Chair: Glaucius Oliva, Universidade de São Paulo, Brazil
Tom Steitz, Yale University, USA
From the Structure and Function of the Ribosome to New Antibiotics

Tuesday – August 25th, 2015

Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Expocenter IV A
Symposium 1 – Ageing
Chair: Efstathios Gonos, National Hellenic Research Foundation, Greece
Hugo Aguilaniu, École Normale Supérieure de Lyon, France.

Molecular Links Between Nutrition, Reproduction, Metabolism and Longevity

Tiago Outeiro, University Med. Center Goettingen, Germany
Glycation: a bitter sweet modification in synucleinopathies
Efstathios Gonos,National Hellenic Research Foundation, Greece
Proteasome Activation as a novel anti-aging strategy
Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Expocenter IV B
Symposium 2 – Protein Structure and Folding
Chair: Richard Garratt, Universidade de São Paulo, IFSC, Brazil
Janet Thornton, European Molecular Biology Laboratory, European Bioinformatics Institute , UK
The evolution of enzyme function
Gabriel Waksman, Institute of Structural and Molecular Biology (ISMB), UK
Structure and molecular biology of secretion nanomachines in Gram-negative bacterial pathogens
Shaker Chuck Farah, Universidade de São Paulo, IQ,Brazil
Toxin delivery by The Xanthomonas Type IV Secretion System
Bonnie Wallace, Institute of Structural and Molecular Biology, Birkbeck College, University of London, UK
Sodium Channels: Structure, Function and Disease
Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Expocenter IV C
Symposium 3 – Science Education “Leopoldo de Meis”
Chair:
Wagner Seixas da Silva, Universidade Federal do Rio de Janeiro
Bruce Alberts, University of California (San Francisco), USA
The Critical Importance of Science Education for Society
Diogo Onofre de Souza, Universidade Federal do Rio Grande do Sul, BrazilThe Relevance of Neuroscience in Evaluation of Students in Classroom
Paulo S.L. Beirão, Universidade Federal de Minas Gerais,BrazilReplacing Prctical Classes with Experimental Projects
Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Iguaçu I – 5th floor
Symposium 4Stem Cells and Cell Therapy
Chair: Stevens Rehen, UFRJ e Instituo D’Or de Pesquisa e Ensino, Brazil
Mayana Zatz, Instituto de Biociências, Universidade de São Paulo, Brazil
Stem Cells Therapy for Neuromuscular Disorders: What Have we Learned?
Marcelo Morales, Instituto de Biofísica, Universidade Federal do Rio de Janeiro, BrazilStem Cell Therapy Research for Respiratory Diseases

Wadih Arap, University of New Mexico, USA
Applications of Phage Display in Stem Dell Research

Stevens Rehen, UFRJ e Instituo D’Or de Pesq e Ensino, Brazil
Reprogramming cells to study mental disorders
Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Iguaçu II – 5th floor
Symposium 5 – Biochemical Society: Energy and Metabolism
Chairs: Fraser MacMillan, University of East Anglia, UK and David Carling, Imperial College London, UK
David Carling, MRC Clinical Sciences Centre, Imperial College London, UK
Regulating energy metabolism: the AMP-activated protein kinase cascade
Richard Cogdell, University of Glagow, UK
How purple photosynthetic bacteria harvest solar energy
Judy Hirst, Mithocondrial Biology Unit, UK
Architecture of mammalian respiratory complex I
Fraser MacMillan, University of East Anglia, UK
Understanding Movement and Mechanism in Membrane Proteins: A Biophysical Spectroscopist’s View
11:00 to 11:30 – Coffee Break
Tuesday – August 25th, 2015 – 11:30 am to 12:30 pm – Room: Expocenter IV
Keynote Lecture 2
Chair: Gregory Petsko
Martin Chalfie, Columbia University Biological Sciences – USA
Determining Neuronal Fate in C. elegans
Tuesday – August 25th, 2015 – 12:30 to 2 pm – Lunch

2:00 to 3:00 pm – Room: Expocenter IV

Keynote Lecture 3
Chair: Angelo Azzi, University of Padua, Italy
Salvador Moncada, The University of Manchester, UK
Nitric oxide, cell bioenergetics and proliferation: exploring some basic mechanisms
3:00 to 3:30 pm – Break Time
Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Expocenter IV A
Symposium 6Portugal-Brazil: Inflamation and Redox Signalling
Chair: João Laranjinha, Universidade de Coimbra, Portugal
Francisco Ambrósio, Universidade de Coimbra, Portugal
Targeting microglia to treat retinal degenerative diseases?
João Laranjinha, Universidade de Coimbra, Portugal
Nitric Oxide-Mediated Neurovascular Coupling In Healthy and Diseased Brain: Sources, Mechanisms and Significance
Leda Q. Vieira, UFMG, Brazil
A matter of life and death: ROS and intracellular parasites
Dario Zamboni, FMRP-USP, Brazil
Inflammasomes in host resistance to intracellular pathogens
Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Expocenter IV B
Symposium 7 – Metabolic Diseases
Chair: Moacir Wajner, Universidade Federal do Rio Grande do Sul, Brazil
Jared Rutter, Uni. Utah, USA
Functionalizing the Unannotated Mitochondrial Proteome
Anthony J. Kettle, University of Otago, New Zealand
Oxidation of Uric Acid as a Barometer of Oxidative Stress
Abel Santamaria, Instituto Nacional de Neurología y Neurocirugía, SSA, Mexico City, Mexico
The role of the kynurenine pathway of tryptophan metabolism in neurodegenerative disorders: experimental and clinical evidence
Moacir Wajner, Universidade Federal do Rio Grande do Sul, Brazil
Disruption of redox and energy homeostasis in fatty acid oxidation disorders: insights from animal and human studies
Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Expocenter IV C
Symposium 8Bioenergy: Cells walls and enzymes
Chair: Marcos Buckeridge, Instituto de Biociências, Universidade de São Paulo, Brazil
Nicholas Carpita, Purdue University’s College of Agriculture, USA
Genetically tailoring the structure of the plant cell wall for advanced bioproducts and biofuels
Igor Polikarpov, Instituto de Física de São Carlos, Universidade de São Paulo, Brazil
Structure Functional Studies of Glycoside Hydrolases
Simon J McQueen-Mason, Centre for Novel Agricultural Products (CNAP), Department of Biology, University of York, UK
Overcoming the digestibility barrier in lignocellulosic plant biomass
Marcos Buckeridge, Instituto de Biociências, Universidade de São Paulo, Brazil
Breaking the Glycomic Code of plant cell walls to improve bioenegy production
Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Iguaçu I – 5th floor
Symposium 9 – Cancer
Chair:
Ricardo J. Giordano, USP-IQ, Brazil
Renata Pasqualini, University of New Mexico, USA
Ligand-Directed Targeting and Molecular Imaging Based on In Vivo Phage Display
José B. Carvalheira, Universidade de Campinas -FCM, Brazil
Obesity-associated cancer: Mechanistic and translational insights
Massimo Loda, Harvard Medical School, USA
Metabolic dependencies in prostate cancer: regulation and targeting of lipogenesis
Robson Q. Monteiro, Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Brazil
Molecular and cellular mechanisms of cancer-associated thrombosis
Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Iguaçu II – 5th floor
Symposium 10 – In Silico Biochemistry
Chair: Roberto Lins, Universidade Federal de Pernambuco, Brazil
Werner Trepow, Uiversidade de Brasília, Brazil
E
lectric fingerprint of voltage sensor domains
Sergio Pantano, Institute Pasteur at Montevideo, Uruguay
Exploring the Open State of Connexin 26 Hemichannels with Coarse-grained Simulations
Ingemar Andre, Lunds University, Sweden
Computational design of proteins/peptides self-assembly
Paulo Sergio Lopes Oliveira, LnBio, Brazil
Challenges in building useful models for macromolecular interactions: a problem for men or machines?
5:30 to 6:00 pm Coffee break
6:00 to 8:00 pm

Poster Session I

7:30 to 8:30 pm General Assembly – All participants are invited (in Portuguese)

Wednesday – August 26th, 2015

Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Expocenter IV A
Symposium 11 – Diabetes
Chair: Mario Saad, Unicamp, Brazil
Amira Klip, University of Toronto, Ontario, Canada
Crosstalk between muscle and immune cells in the generation of insulin resistance
Mari C. Sogayar, Núcleo de Terapia Celular e Molecular, Universidade de São Paulo, Brazil
Tackling the challenges posed by type 1 Diabetes mellitus: several ways to skin a cat
Décio Eizirik, Medical Faculty, Universite Libre de Bruxelles (ULB)
Dangerous Liaisons – candidate genes, pancreatic beta cells and the innate immune system in T1D
Mario Saad, Faculdade de Ciências Médicas, Universidade de Campinas, Brazil
Molecular mechanisms of insulin resistance
Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Expocenter IV B
Symposium 12 – Emerging Viral Disease and Vaccines
Chair: Andrea T. Da Poian, Universidade Federal do Rio de Janeiro, Brazil
Jorge Elias Kalil Filho, Instituto do Coração, Universidad de São Paulo, Brazil

Michael Kurilla, NIH-NIAID, USA
Addressing Emerging Viral Diseases with Vaccines and other Medical Countermeasures

Marcelo Lopez-Lastra, Pontificia Universidad Católica de Chile
Novel insight into Andes Hantavirus-host relationship; from basic to translational science
Andrea T. Da Poian, Universidade Federal do Rio de Janeiro, Brazil
Beyond the structural function of dengue virus capsid protein: the role of its interaction with lipids in viral entry and replication
Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Expocenter IV C
Symposium 13Cell: Life and Death
Chair: Miguel De La Rosa, Universidad de Sevilla, Spain
Ricardo Weinlich,Instituto de Ensino e Pesquisa do Hospital Israelita Albert Einstein, BrazilPulling the necroptotic trigger
Maria I Vaccaro, Universidad de Buenos Aires, Argentina
Autophagy in Complex Diseases. The role of VMP1, a novel autophagy-related protein
Miguel De La Rosa, Universidad de Sevilla, Spain
A Common Cytochorme c-centred Signalosome for Programmed Cell Death in Humans and Plants
Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Iguaçu I – 5th floor
Symposium 14 – Molecular Mechanisms in Neurodegenerative Diseases
Chair: Yraima Cordeiro, Faculdade de Farmácia da UFRJ, Brasil
Débora Foguel, Instituto de Bioquimica Médica, Universidade Federal do Rio de Janeiro, Brazil
Studies with the Amyloidogenic Protein Transthyretin: from the Patients to the Protein
Fernanda G. De Felice, Instituto de Bioquimica Médica, Universidade Federal do Rio de Janeiro, Brazil
Defective brain insulin signaling and memory impairment in Alzheimer’s disease.
Claudio Soto, University of Texas, USA
Spreading of Misfolded Protein Aggregates as a Pathogenic Mechanism of Neurodegenerative diseases
Byron Caughey, National Institute of Allergy and Infectious Diseases (NIAID), USA
Prion Structures And The Ultrasensitive Detection of Misfolded Protein Aggregates By Seeded Fibrillization
Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Iguaçu II – 5th floor
Symposium 15 – 19th Prize for Young Talent for Life Science
Chair: José Roberto Meyer Fernandes, Universidade Federal do Rio de Janeiro, Brazil
Bruno Chausse, Instituto de Química, USP
Intermittent Fasting Changes Energetic Metabolism by Induction of Hypothalamic and Redox Modifications
Constanza Feliziani, IMMEC, Conicet, Argentina
The giardial enth protein participates in lysosomal protein trafficking and endocytosis
Mariana Figueiredo Rodrigues, UFRJ, Brazil
The changing energy profile of melanoma cells as they progress towards metastasis.
Roberta de Paula Martins, UFSC, Brazil
Potential inhibitory effects of neopterin on inflammasome activation in human primary astrocytes

Thiago Antonio de O. Mendes, UFMG, Brazil
Metabolic changes of pathogenic and nonpathogenic leishmania species during host cell infection by integration of mathematical models, quantitative proteomics and untargeted 1h-NMR

11:00 to 11:30 – Coffee Break

Wednesday – August 26th, 2015 - 11:30 am to 12:30 pm – Room: Expocenter IV
FEBS Keynote Lecture 4
Chair: Helena B. Nader, Unifesp, Brazil
Günther Meister, University of Regensburg, Germany
RNA binding proteins as modulators of coding and non-coding RNA pathways

12:30 to 2 pm – Lunch

Wednesday – August 26th, 2015 - 2:00 to 3:00 pm – Room: Expocenter IV
Keynote Lecture 5
Chair: Joan J. Guinovart, Institute of Research in Biomedicine, Barcelona, Spain
Kurt Wüthrich, The Scripps Research Institute, La Jolla, CA, USA
NMR Spectroscopy in Molecular Structural Biology
3:00 to 3:30 pm – Break Time
Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Expocenter IV A
Symposium 16 – Biochemistry and Molecular Biology of Arthropods
Chair: Walter R. Terra, Instituto de Química, Universidade de São Paulo, Brazil
José Marcos Chaves Ribeiro, NIAID, USA
Kratagonists: an Ubiquitous Class of Pharmacological Inhibitors Found in the Saliva of Blood Sucking Arthropods
Marcio de Castro Silva Filho, Esalq-USP, Brazil
Synergistic action of opportunistic fungi and sugarcane borer Diatraea saccharalis promotes red-rot disease in sugarcane
Elena Elpidina, Moscow State University, Moscow
Serine and Cysteine Peptidases in Insects: Structure and Functions
Pedro de Oliveira, Instituto de Bioquimica Médica, Universidade Federal do Rio de Janeiro, Brazil
Aromatic aminoacid degradation has a major role in the adaptation of insect vectors to a blood feeding way of life
Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Expocenter IV B
Symposium 17 – Spatial Distribution of Celullar Processes
Chair: Philipe Nagley, Monash University, Australia
James Davie, University of Manitoba, Canada
Epigenomics, dynamics histone acetylation and the regulation of gene expression
Orian Shirihai, Boston University, USA
Mitochondrial dynamics in the regulation of energy efficiency and quality control
Akihiko Nakano,The University of Tokyo, JapanSuper-resolution Confocal Live Imaging Microscopy (SCLIM) as a Tool to Understand Mechanisms of Membrane Trafficking
Flavio Silva Junqueira de Souza, Institute for Molecular Biology and Genetic Engineering, Argentina
Enhancers, transcription factors and gene regulation in the vertebrate hypothalamus
Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Expocenter IV C
Symposium 18 – Biomaterials and Synthetic Biology
Chair: José Mauro Granjeiro, Universidade Federal Fluminense, Brazil
Rolf Alexander Prade, Oklahoma State University, USA
Enzyme Biomass Combustion by Shared Oxidation & Hydrolysis Mechanisms
Mateus Schreiner Garcez Lopes,Innovation in Renewable Technologies – Braskem, Brazil
Driving Innovation with Renewable Chemicals Platform – the role of synthetic biology in the petrochemical industry
José Mauro Granjeiro, Universidade Federal Fluminense, Brazil
From the bench to the bedside: biodegradable carbonate apatite for bone repair
Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Iguaçu I – 5th floor
Symposium 19 – Neurochemistry
Chair: João B.T. Rocha, Universidade Federal de Santa Maria, Brazil
Svetlana Antonyuk, University of Liverpool, UK
Structural studies of proteins involved in neurodegenerative diseases: a road from protein aggregates to treatment
Francisco José Barrantes, University of Argentina-CONICET, Argentina
Cholesterol modulates structural and dynamic properties of nicotinic acetylcholine receptors

Andrea C. Paula Lima, Universidad de Chile
Role of ryr2-mediated calcium release in synaptic plasticity defects and memory loss induced by soluble abeta oligomers

João B.T. Rocha, Universidade Federal de Santa Maria, Brazil
Synthetic Organoseleno compounds as mimetics of Selenoproteins
Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Iguaçu II – 5th floor
Symposium 20 – PABMB: Teaching biochemistry in a connected world
Chair: Miguel Castanho, Universidade de Lisboa, Portugal
Andrea T. Da Poian, Universidade Federal do Rio de Janeiro, Brazil
Hands-on inquiry-based biochemistry courses for improving scientific literacy of school teachers and students
Raul Herrera, Universidad de Talca, IBVB, Chile
Keeping 3D resources in the web to learn on protein structure
Eduardo Galembeck, Universidade de Campinas, Brazil
How Apps-Embedded Assessment can contribute to learning outcomes mapping
Jose Sotelo, Montevideo, Uruguay
Using “raw” online data derived from global gene expression experiments for posgraduate teaching activities
5:30 to 6:00 pm Coffee break
6:00 to 8:00 pm

Poster Session II

Thursday – August 27th, 2015

Thursday – August 27th, 2015 – 9:00 to 11:00 am – Room: Expocenter IV A
Symposium 21Uruguay-Brazil: Biochemistry of Free Radicals and Oxidative Stress
Chair: José Sotelo, Uruguay
Omar Borsani, Universidad de La Republica, Uruguay
Plant drought responses mediated by nitro-oxidative stress
Beatriz Alvarez, Universidad de La Republica, Uruguay
Reactivty of hydrogen sulfide towards biological oxidants, disulfides and sulfenic acids
Lucia Piacenza, Universidad de La Republica, Uruguay
Antioxidant Enzymes of Trypanosoma cruzi as virulent factors for Chagas Disease
Lia Nakao, Universidade Federal do Paraná, Brazil
Novel roles of the extracellular flavoprotein quiescin/sulfhydryl oxidase 1 (QSOX1)
Thursday – August 27th, 2015 – 9:00 to 11:00 am – Room: Expocenter IV B
Symposium 22Cell Signalling
Chair: Jörg Kobarg, Unicamp, Brazil
Rony Seger, Weizmann Institute of Science, Israel
The Nuclear Translocation of MAPKs: A Novel Drug Target for Signaling-Related Diseases
Alexandra Newton, University of California (San Diego), USA
Reversing the paradigm: protein kinase C as a tumor suppressor
Deborah Schechtman, Universidade de São Paulo, Instituto de Química, Brazil
Protein Kinases Read “Braille”
Jörg Kobarg, Universidade de Campinas, Brazil
The involvement of members of the human family of Nek kinases in the regulation of the cell cycle, the DNA damage response and beyond
Thursday – August 27th, 2015 – 9:00 to 11:00 am – Room: Expocenter IV C
Symposium 23 – Plant Biochemistry and Molecular Biology
Chair: Pio Colepicolo, USP-IQ
Jose Manuel Estevez, Universidad de Buenos Aires, Argentina
Ca+2 and ROS master regulators of single plant cell expansion
Eric Lam, Rutgers, The State University of New Jersey, USA
Paving the foundation for the novel aquatic agricultural platform of duckweed with genomics
Jesus Aparecido Ferro, Universidade Estadual Paulista Júlio de Mesquita Filho, Brazil
Plant–pathogen interactions in citrus canker: An integrated view
Chunlin Long, College of Life and Environmental Sciences, Minzu University of China, China
Genetic diversity of buckwheat in different farming and cultural environments in the Himalayas
Thursday – August 27th, 2015 – 9:00 to 11:00 am – Room: Iguaçu I – 5th floor
Symposium 24Nanobiotechnology
Chair: Henrique Eisi Toma , IQ- Universidade de São Paulo, Brazil
Marin van Heel, Leiden University / Imperial College London
Structure and Dynamics of Macromolecular Machines by Single Particle Cryo-EM
Valtencir Zucolotto, IFSC- Universidade de São Paulo, Brazil
Advances in Nanomedicine and Nanotoxicology: Novel Nanomaterials for Diagnosis and Therapy
Ehud Gazit, Tel Aviv University, Israel
Molecular Self-Assembly of Short Peptides and Metabolites: From Amyloid and Metabolic Diseases to New Biomaterials and Nanotechnology
Henrique Eisi Toma, Instituto de Química, Universidade de São Paulo, Brazil
Nanoparticles and Biomolecules: an inspiring partnership
11:00 to 11:30 – Coffee Break
Thursday – August 27th, 2015 – 11:30 am to 12:30 pm: Expocenter IV
Keynote Lecture 6
Chair: Michael P. Walsh, University of Calgary, Canada
José Onuchic, Rice University, USA
From structure to function: the convergence of structure based models and co-evolutionary information
12:30 to 2 pm – LunchThursday – August 27th, 2015 – 2:00 to 3:00 pm: Expocenter IV
Keynote Lecture 7
Chair: Hugo J. Maccioni, PABMB President and Universidad Nacional de Cordoba, Argentina
Johann Deisenhofer, The University of Texas Southwestern Medical Center and German Academy of Natural Scientists Leopoldina

Structural Biology of Photosynthetic Light Reactions

3:00 to 3:30 pm – Break Time
Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Expocenter IV A
Symposium 26 – Protein Misfolding Diseases
Chair: Sergio T. Ferreira, Universidade Federal do Rio de Janeiro, Brazil
Yuji Goto, University of Osaka, Japan
Supersaturation-limited Protein Misfolding Revealed by Ultrasonication

Peter Walter, University of California, San Francisco, CA, USA
From Protein Folding to Cognition:The Serendipitous Path of Discovery

Harm Kampinga, University of Groningen , The Netherlands
Functional specificity of heat shock proteins in dealing with protein aggregation diseases
Sergio T. Ferreira, Universidade Federal do Rio de Janeiro, Brazil
Brain inflammation links memory impairment and depressive-like behavior induced by Alzheimer’s ABeta oligomers in rodents
Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Expocenter IV B
Symposium 27 – Redox Signalling
Chair: Rafael Radi, Udelar, Uruguay
Francisco Laurindo, Incor-FM- Universidade de São Paulo, Brazil
Protein disulfide isomerases in redox signaling and homeostasis: mechanisms and pathophysiological implications
Ohara Augusto, IQ- Universidade de São Paulo, Brazil
Protein oxidation: from redox signaling to protein aggregation.
Rafael Radi, Universidad de La Republica, Udelar, Uruguay
Advances in the biochemistry of protein tyrosine nitration
Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Expocenter IV C
Symposium 28 – Cell Differenciation
Chair: Henning Ulrich, Universidade de São Paulo -IQ, Brazil
Lakshmi Devi, Icahn School of Medicine at Mount Sinai, New York
Signaling Networks in Neuronal Differentiation: A Role for G Protein-coupled Receptor Heterodimers in Modulating Signaling

Ivan Velasco, UNAM-Universidad Nacional Autonoma del Mexico – IFC, Mexico
Enhancing maturation, axonal growth and survival of Embryonic Stem cell-derived neurons

James Manley, Columbia University, USA
Regulated Processing Of mRNA Precursors During Cell Differentiation

Henning Ulrich, Universidade de São Paulo, Brazil
Promotion of Neurogenesis and Brain Repair by Bradykinin

Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Room: Iguaçu I – 5th Floor
Symposium 29 – Portugal-Brazil: Biomembranes and Transporters: New Targets for Old Diseases
Chair: Iolanda M. Cuccovia, Universidade de São Paulo -IQ, Brazil
Graça Soveral, Universidade de Lisboa, Portugal
Aquaporin channels in membranes: therapeutic targets for chronic diseases
Miguel Castanho, Universidade de Lisboa, Portugal
Biomembranes as drug targets for antimicrobial peptides: from vesicles to bacteria
Celso Caruso Neves, Universidade Federal do Rio de Janeiro, Brazil
Albumin induces renal disease: role of mTOR pathway
Iolanda M. Cuccovia, Universidade de São Paulo IQ, Brazil
Polymer- and Peptide-membrane interactions in model systems
Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Room: Iguaçu II – 5th Floor
Symposium 30 – Inflammation
Chair: Patrícia Bozza, Fiocruz-IOC, Brazil
Adi Kimchi, The Weizmann Institute, Israel
The Protein Interaction Map of Apoptosis and Autophagy: From Basic Science to a Therapeutic Vision
Fernando Cunha, FMRP-Universidade de São Paulo, Brazil
Mechanisms involved in the innate immune-dysfunction induced by severe sepsis
Andrew S Weyric, University of Utah

Novel Functions of Platelets in Health and Infectious Disease

Patrícia Bozza, Fiocruz-IOC, Brazil
Mechanisms and Functions of Lipid Droplets in Cell Signaling, Inflammation and Cancer
5:30 to 6:00 pm Coffee break
6:00 to 8:00 pm

Poster Session III

Friday – August 28th, 2015

Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Expocenter IV A
Symposium 31 – Infectious diseases
Chair: Selma Jerônimo, Universidade Federal do Rio Grande do Norte, Brazil
Bianca Zingales, Instituto de Química, Universidade de São Paulo, Brazil
The Molecular Epidemiology of Trypanosoma cruzi and Drug Discovery
Fernando Goldbaum, Inmunología y Microbiología Molecular, Fundación Instituto Leloir, Argentina
Development of a Prophylactic Vaccine and Therapeutic Antibodies against Hemolytic Uremic Syndrome using Protein and Antibody Engineering
K. Muniyappa, Indian Institute of Science, India
Negative Regulation of Homologous Recombination in Mycobacteria: Insights from Single-molecule Studies
Selma Jerônimo, Universidade Federal do Rio Grande do Norte, Brazil
Altered metabolism in tropical diseases: the case of visceral leishmaniasis
Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Expocenter IV B

Symposium 32 – Shedding light on life

Chair: Maurício S Baptista, Universidade de São Paulo, Brazil

Life is connected to light in several ways. From photosynthesis to the health of humans and being present in countless applications, light have revolutionized our society. In recognition for this and expecting that light will play an increasing role in future technologies, UNESCO decided that 2015 is the INTERNATIONAL YEAR OF LIGHT SBBq prepared this symposium to bring to our society scientific novelties in this field, hoping to foster high-level discussions related with light induced phenomenon

Enrico Gratton, University of California – Irvine, USA
Chromatin structure and dynamics
Robert Tabita, Ohio State University, USA
Structure, function, and modification of microbial Rubisco From Cultured and uncultured organisms
Etelvino J.H. Bechara,Universidade de São Paulo, Brazil
Photochemistry without Light: Mechanisms and Biological Responses
Maurício S Baptista,Universidade de São Paulo, Brazil
Exploiting the “double-edged sword” roles of Visible light
Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Expocenter IV C
Symposium 33 – Obesity
Chair: Licio Velloso, Universidade de Campinas, Brazil
Deborah Kurrash, University of Calgary, Canada
Genetic Programs that Govern Development of Hypothalamic Satiety Centres
Miriam Cnop , Universite Libre de Bruxelles, Belgium
A choice of death: beta cell failure in diabetes
Licio Velloso, Universidade de Campinas, BrazilRewiring the damaged obese hypothalamus with polyunsaturated fats
Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Iguaçu I – 5th Floor
Symposium 34 – Cancer
Chair: Roger Chammas, Faculdade de Medicina, Universidade de São Paulo, Brazil
Carol Prives, Columbia University, USA
The opposing functions of wild-type and mutant forms of p53
Anamaria Aranha Camargo, Instituto Ludwig, Brazil
SIGIRR/TIR8: a new player in the crosstalk between breast tumours and the immune system
M. Iqbal Parker, International Centre for Genetic Engineering and Biotechnology (ICGEB), South Africa
Endogenous and Exogenous viral sequences in Oesophageal cancer
Roger Chammas, Faculdade de Medicina, Universidade de São Paulo, Brazil
Revisiting the cellular and molecular basis of melanoma chemoresistance: opportunities to innovative combination therapy
Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Iguaçu I – 5th Floor>
Symposium 35 – Protein Dynamics and Function
Chair: Fabio C.L. de Almeida, Universidade Federal do Rio de Janeiro
Stefano Ciurli, University of Bologna, Italy
Structure and dynamics of Jaburetox, an intrinsically disordered polypeptide derived from jack bean urease
Dmitry Korzhnev, University of Connecticut Health Center, USA
Interaction Network Of Translesion Synthesis Dna Polymerases

Alejandro Buschiazzo, Instituto Pasteur, Uruguay
The Crystal Structure Of The Native Capsid From Bovine Leukemia Virus: Retroviral Capsids Are Plastic

Fabio C.L. de Almeida, Universidade Federal do Rio de Janeiro, Brazil
Dissection of the water cavity of yeast thioredoxin
11:00 to 11:30 – Coffee Break
Friday – August 28th, 2015 – 11:30 am to 12:30 pm: Room: Expocenter IV
Keynote Lecture
Chair: Jerson Lima da Silva, Universidade Federal do Rio de Janeiro, Brazil
Bruce Alberts, University of California (San Francisco), USA
The Problems and Challenges in Biomedical Sciences
Friday – August 28th, 2015 – 12:30 to 13:00 pm: Expocenter IV
Closing Ceremony and SBBq Awards
The Announcement of SBBq Awards for best posters presentation and the 19th Prize for Young Talent in Life Sciences