Scientific Program
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Monday – August 24th, 2015 |
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| 5:30 to 6:00 pm | Opening Ceremony |
| 6:00 to 7:00 pm | Chair: Glaucius Oliva, Universidade de São Paulo, Brazil |
| Tom Steitz, Yale University, USA From the Structure and Function of the Ribosome to New Antibiotics |
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Tuesday – August 25th, 2015 |
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| Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Expocenter IV A | |
| Symposium 1 – Ageing Chair: Efstathios Gonos, National Hellenic Research Foundation, Greece |
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| Hugo Aguilaniu, École Normale Supérieure de Lyon, France.
Molecular Links Between Nutrition, Reproduction, Metabolism and Longevity |
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| Tiago Outeiro, University Med. Center Goettingen, Germany Glycation: a bitter sweet modification in synucleinopathies |
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| Efstathios Gonos,National Hellenic Research Foundation, Greece Proteasome Activation as a novel anti-aging strategy |
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| Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Expocenter IV B | |
| Symposium 2 – Protein Structure and Folding Chair: Richard Garratt, Universidade de São Paulo, IFSC, Brazil |
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| Janet Thornton, European Molecular Biology Laboratory, European Bioinformatics Institute , UK The evolution of enzyme function |
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| Gabriel Waksman, Institute of Structural and Molecular Biology (ISMB), UK Structure and molecular biology of secretion nanomachines in Gram-negative bacterial pathogens |
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| Shaker Chuck Farah, Universidade de São Paulo, IQ,Brazil Toxin delivery by The Xanthomonas Type IV Secretion System |
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| Bonnie Wallace, Institute of Structural and Molecular Biology, Birkbeck College, University of London, UK Sodium Channels: Structure, Function and Disease |
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| Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Expocenter IV C | |
| Symposium 3 – Science Education “Leopoldo de Meis” Chair: Wagner Seixas da Silva, Universidade Federal do Rio de Janeiro |
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| Bruce Alberts, University of California (San Francisco), USA The Critical Importance of Science Education for Society |
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| Diogo Onofre de Souza, Universidade Federal do Rio Grande do Sul, BrazilThe Relevance of Neuroscience in Evaluation of Students in Classroom | |
| Paulo S.L. Beirão, Universidade Federal de Minas Gerais,BrazilReplacing Prctical Classes with Experimental Projects | |
| Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Iguaçu I – 5th floor | |
| Symposium 4 – Stem Cells and Cell Therapy Chair: Stevens Rehen, UFRJ e Instituo D’Or de Pesquisa e Ensino, Brazil |
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| Mayana Zatz, Instituto de Biociências, Universidade de São Paulo, Brazil Stem Cells Therapy for Neuromuscular Disorders: What Have we Learned? |
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| Marcelo Morales, Instituto de Biofísica, Universidade Federal do Rio de Janeiro, BrazilStem Cell Therapy Research for Respiratory Diseases | |
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Wadih Arap, University of New Mexico, USA |
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| Stevens Rehen, UFRJ e Instituo D’Or de Pesq e Ensino, Brazil Reprogramming cells to study mental disorders |
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| Tuesday – August 25th, 2015 – 9 am to 11 am – Room: Iguaçu II – 5th floor | |
| Symposium 5 – Biochemical Society: Energy and Metabolism Chairs: Fraser MacMillan, University of East Anglia, UK and David Carling, Imperial College London, UK |
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| David Carling, MRC Clinical Sciences Centre, Imperial College London, UK Regulating energy metabolism: the AMP-activated protein kinase cascade |
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| Richard Cogdell, University of Glagow, UK How purple photosynthetic bacteria harvest solar energy |
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| Judy Hirst, Mithocondrial Biology Unit, UK Architecture of mammalian respiratory complex I |
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| Fraser MacMillan, University of East Anglia, UK Understanding Movement and Mechanism in Membrane Proteins: A Biophysical Spectroscopist’s View |
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| 11:00 to 11:30 – Coffee Break | |
| Tuesday – August 25th, 2015 – 11:30 am to 12:30 pm – Room: Expocenter IV | |
| Keynote Lecture 2 Chair: Gregory Petsko |
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| Martin Chalfie, Columbia University Biological Sciences – USA Determining Neuronal Fate in C. elegans |
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| Tuesday – August 25th, 2015 – 12:30 to 2 pm – Lunch | |
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2:00 to 3:00 pm – Room: Expocenter IV |
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| Keynote Lecture 3 Chair: Angelo Azzi, University of Padua, Italy |
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| Salvador Moncada, The University of Manchester, UK Nitric oxide, cell bioenergetics and proliferation: exploring some basic mechanisms |
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| 3:00 to 3:30 pm – Break Time | |
| Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Expocenter IV A | |
| Symposium 6 – Portugal-Brazil: Inflamation and Redox Signalling Chair: João Laranjinha, Universidade de Coimbra, Portugal |
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| Francisco Ambrósio, Universidade de Coimbra, Portugal Targeting microglia to treat retinal degenerative diseases? |
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| João Laranjinha, Universidade de Coimbra, Portugal Nitric Oxide-Mediated Neurovascular Coupling In Healthy and Diseased Brain: Sources, Mechanisms and Significance |
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| Leda Q. Vieira, UFMG, Brazil A matter of life and death: ROS and intracellular parasites |
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| Dario Zamboni, FMRP-USP, Brazil Inflammasomes in host resistance to intracellular pathogens |
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| Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Expocenter IV B | |
| Symposium 7 – Metabolic Diseases Chair: Moacir Wajner, Universidade Federal do Rio Grande do Sul, Brazil |
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| Jared Rutter, Uni. Utah, USA Functionalizing the Unannotated Mitochondrial Proteome |
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| Anthony J. Kettle, University of Otago, New Zealand Oxidation of Uric Acid as a Barometer of Oxidative Stress |
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| Abel Santamaria, Instituto Nacional de Neurología y Neurocirugía, SSA, Mexico City, Mexico The role of the kynurenine pathway of tryptophan metabolism in neurodegenerative disorders: experimental and clinical evidence |
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| Moacir Wajner, Universidade Federal do Rio Grande do Sul, Brazil Disruption of redox and energy homeostasis in fatty acid oxidation disorders: insights from animal and human studies |
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| Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Expocenter IV C | |
| Symposium 8 – Bioenergy: Cells walls and enzymes Chair: Marcos Buckeridge, Instituto de Biociências, Universidade de São Paulo, Brazil |
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| Nicholas Carpita, Purdue University’s College of Agriculture, USA Genetically tailoring the structure of the plant cell wall for advanced bioproducts and biofuels |
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| Igor Polikarpov, Instituto de Física de São Carlos, Universidade de São Paulo, Brazil Structure Functional Studies of Glycoside Hydrolases |
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| Simon J McQueen-Mason, Centre for Novel Agricultural Products (CNAP), Department of Biology, University of York, UK Overcoming the digestibility barrier in lignocellulosic plant biomass |
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| Marcos Buckeridge, Instituto de Biociências, Universidade de São Paulo, Brazil Breaking the Glycomic Code of plant cell walls to improve bioenegy production |
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| Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Iguaçu I – 5th floor | |
| Symposium 9 – Cancer Chair: Ricardo J. Giordano, USP-IQ, Brazil |
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| Renata Pasqualini, University of New Mexico, USA Ligand-Directed Targeting and Molecular Imaging Based on In Vivo Phage Display |
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| José B. Carvalheira, Universidade de Campinas -FCM, Brazil Obesity-associated cancer: Mechanistic and translational insights |
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| Massimo Loda, Harvard Medical School, USA Metabolic dependencies in prostate cancer: regulation and targeting of lipogenesis |
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| Robson Q. Monteiro, Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Brazil Molecular and cellular mechanisms of cancer-associated thrombosis |
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| Tuesday – August 25th, 2015 – 3:30 to 5:30 pm – Room: Iguaçu II – 5th floor | |
| Symposium 10 – In Silico Biochemistry Chair: Roberto Lins, Universidade Federal de Pernambuco, Brazil |
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| Werner Trepow, Uiversidade de Brasília, Brazil Electric fingerprint of voltage sensor domains |
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| Sergio Pantano, Institute Pasteur at Montevideo, Uruguay Exploring the Open State of Connexin 26 Hemichannels with Coarse-grained Simulations |
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| Ingemar Andre, Lunds University, Sweden Computational design of proteins/peptides self-assembly |
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| Paulo Sergio Lopes Oliveira, LnBio, Brazil Challenges in building useful models for macromolecular interactions: a problem for men or machines? |
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| 5:30 to 6:00 pm | Coffee break |
| 6:00 to 8:00 pm |
Poster Session I |
| 7:30 to 8:30 pm | General Assembly – All participants are invited (in Portuguese) |
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Wednesday – August 26th, 2015 |
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| Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Expocenter IV A | |
| Symposium 11 – Diabetes Chair: Mario Saad, Unicamp, Brazil |
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| Amira Klip, University of Toronto, Ontario, Canada Crosstalk between muscle and immune cells in the generation of insulin resistance |
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| Mari C. Sogayar, Núcleo de Terapia Celular e Molecular, Universidade de São Paulo, Brazil Tackling the challenges posed by type 1 Diabetes mellitus: several ways to skin a cat |
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| Décio Eizirik, Medical Faculty, Universite Libre de Bruxelles (ULB) Dangerous Liaisons – candidate genes, pancreatic beta cells and the innate immune system in T1D |
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| Mario Saad, Faculdade de Ciências Médicas, Universidade de Campinas, Brazil Molecular mechanisms of insulin resistance |
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| Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Expocenter IV B | |
| Symposium 12 – Emerging Viral Disease and Vaccines Chair: Andrea T. Da Poian, Universidade Federal do Rio de Janeiro, Brazil |
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| Jorge Elias Kalil Filho, Instituto do Coração, Universidad de São Paulo, Brazil | |
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Michael Kurilla, NIH-NIAID, USA |
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| Marcelo Lopez-Lastra, Pontificia Universidad Católica de Chile Novel insight into Andes Hantavirus-host relationship; from basic to translational science |
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| Andrea T. Da Poian, Universidade Federal do Rio de Janeiro, Brazil Beyond the structural function of dengue virus capsid protein: the role of its interaction with lipids in viral entry and replication |
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| Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Expocenter IV C | |
| Symposium 13 – Cell: Life and Death Chair: Miguel De La Rosa, Universidad de Sevilla, Spain |
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| Ricardo Weinlich,Instituto de Ensino e Pesquisa do Hospital Israelita Albert Einstein, BrazilPulling the necroptotic trigger | |
| Maria I Vaccaro, Universidad de Buenos Aires, Argentina Autophagy in Complex Diseases. The role of VMP1, a novel autophagy-related protein |
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| Miguel De La Rosa, Universidad de Sevilla, Spain A Common Cytochorme c-centred Signalosome for Programmed Cell Death in Humans and Plants |
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| Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Iguaçu I – 5th floor | |
| Symposium 14 – Molecular Mechanisms in Neurodegenerative Diseases Chair: Yraima Cordeiro, Faculdade de Farmácia da UFRJ, Brasil |
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| Débora Foguel, Instituto de Bioquimica Médica, Universidade Federal do Rio de Janeiro, Brazil Studies with the Amyloidogenic Protein Transthyretin: from the Patients to the Protein |
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| Fernanda G. De Felice, Instituto de Bioquimica Médica, Universidade Federal do Rio de Janeiro, Brazil Defective brain insulin signaling and memory impairment in Alzheimer’s disease. |
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| Claudio Soto, University of Texas, USA Spreading of Misfolded Protein Aggregates as a Pathogenic Mechanism of Neurodegenerative diseases |
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| Byron Caughey, National Institute of Allergy and Infectious Diseases (NIAID), USA Prion Structures And The Ultrasensitive Detection of Misfolded Protein Aggregates By Seeded Fibrillization |
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| Wednesday – August 26th, 2015 - 9 am to 11 am – Room: Iguaçu II – 5th floor | |
| Symposium 15 – 19th Prize for Young Talent for Life Science Chair: José Roberto Meyer Fernandes, Universidade Federal do Rio de Janeiro, Brazil |
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| Bruno Chausse, Instituto de Química, USP Intermittent Fasting Changes Energetic Metabolism by Induction of Hypothalamic and Redox Modifications |
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| Constanza Feliziani, IMMEC, Conicet, Argentina The giardial enth protein participates in lysosomal protein trafficking and endocytosis |
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| Mariana Figueiredo Rodrigues, UFRJ, Brazil The changing energy profile of melanoma cells as they progress towards metastasis. |
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| Roberta de Paula Martins, UFSC, Brazil Potential inhibitory effects of neopterin on inflammasome activation in human primary astrocytes |
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Thiago Antonio de O. Mendes, UFMG, Brazil |
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11:00 to 11:30 – Coffee Break |
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| Wednesday – August 26th, 2015 - 11:30 am to 12:30 pm – Room: Expocenter IV | |
| FEBS Keynote Lecture 4 Chair: Helena B. Nader, Unifesp, Brazil |
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| Günther Meister, University of Regensburg, Germany RNA binding proteins as modulators of coding and non-coding RNA pathways |
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12:30 to 2 pm – Lunch |
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| Wednesday – August 26th, 2015 - 2:00 to 3:00 pm – Room: Expocenter IV | |
| Keynote Lecture 5 Chair: Joan J. Guinovart, Institute of Research in Biomedicine, Barcelona, Spain |
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| Kurt Wüthrich, The Scripps Research Institute, La Jolla, CA, USA NMR Spectroscopy in Molecular Structural Biology |
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| 3:00 to 3:30 pm – Break Time | |
| Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Expocenter IV A | |
| Symposium 16 – Biochemistry and Molecular Biology of Arthropods Chair: Walter R. Terra, Instituto de Química, Universidade de São Paulo, Brazil |
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| José Marcos Chaves Ribeiro, NIAID, USA Kratagonists: an Ubiquitous Class of Pharmacological Inhibitors Found in the Saliva of Blood Sucking Arthropods |
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| Marcio de Castro Silva Filho, Esalq-USP, Brazil Synergistic action of opportunistic fungi and sugarcane borer Diatraea saccharalis promotes red-rot disease in sugarcane |
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| Elena Elpidina, Moscow State University, Moscow Serine and Cysteine Peptidases in Insects: Structure and Functions |
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| Pedro de Oliveira, Instituto de Bioquimica Médica, Universidade Federal do Rio de Janeiro, Brazil Aromatic aminoacid degradation has a major role in the adaptation of insect vectors to a blood feeding way of life |
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| Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Expocenter IV B | |
| Symposium 17 – Spatial Distribution of Celullar Processes Chair: Philipe Nagley, Monash University, Australia |
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| James Davie, University of Manitoba, Canada Epigenomics, dynamics histone acetylation and the regulation of gene expression |
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| Orian Shirihai, Boston University, USA Mitochondrial dynamics in the regulation of energy efficiency and quality control |
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| Akihiko Nakano,The University of Tokyo, JapanSuper-resolution Confocal Live Imaging Microscopy (SCLIM) as a Tool to Understand Mechanisms of Membrane Trafficking | |
| Flavio Silva Junqueira de Souza, Institute for Molecular Biology and Genetic Engineering, Argentina Enhancers, transcription factors and gene regulation in the vertebrate hypothalamus |
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| Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Expocenter IV C | |
| Symposium 18 – Biomaterials and Synthetic Biology Chair: José Mauro Granjeiro, Universidade Federal Fluminense, Brazil |
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| Rolf Alexander Prade, Oklahoma State University, USA Enzyme Biomass Combustion by Shared Oxidation & Hydrolysis Mechanisms |
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| Mateus Schreiner Garcez Lopes,Innovation in Renewable Technologies – Braskem, Brazil Driving Innovation with Renewable Chemicals Platform – the role of synthetic biology in the petrochemical industry |
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| José Mauro Granjeiro, Universidade Federal Fluminense, Brazil From the bench to the bedside: biodegradable carbonate apatite for bone repair |
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| Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Iguaçu I – 5th floor | |
| Symposium 19 – Neurochemistry Chair: João B.T. Rocha, Universidade Federal de Santa Maria, Brazil |
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| Svetlana Antonyuk, University of Liverpool, UK Structural studies of proteins involved in neurodegenerative diseases: a road from protein aggregates to treatment |
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| Francisco José Barrantes, University of Argentina-CONICET, Argentina Cholesterol modulates structural and dynamic properties of nicotinic acetylcholine receptors |
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Andrea C. Paula Lima, Universidad de Chile |
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| João B.T. Rocha, Universidade Federal de Santa Maria, Brazil Synthetic Organoseleno compounds as mimetics of Selenoproteins |
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| Wednesday – August 26th, 2015 - 3:30 to 5:30 pm – Room: Iguaçu II – 5th floor | |
| Symposium 20 – PABMB: Teaching biochemistry in a connected world Chair: Miguel Castanho, Universidade de Lisboa, Portugal |
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| Andrea T. Da Poian, Universidade Federal do Rio de Janeiro, Brazil Hands-on inquiry-based biochemistry courses for improving scientific literacy of school teachers and students |
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| Raul Herrera, Universidad de Talca, IBVB, Chile Keeping 3D resources in the web to learn on protein structure |
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| Eduardo Galembeck, Universidade de Campinas, Brazil How Apps-Embedded Assessment can contribute to learning outcomes mapping |
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| Jose Sotelo, Montevideo, Uruguay Using “raw” online data derived from global gene expression experiments for posgraduate teaching activities |
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| 5:30 to 6:00 pm | Coffee break |
| 6:00 to 8:00 pm |
Poster Session II |
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Thursday – August 27th, 2015 |
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| Thursday – August 27th, 2015 – 9:00 to 11:00 am – Room: Expocenter IV A | |
| Symposium 21 – Uruguay-Brazil: Biochemistry of Free Radicals and Oxidative Stress Chair: José Sotelo, Uruguay |
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| Omar Borsani, Universidad de La Republica, Uruguay Plant drought responses mediated by nitro-oxidative stress |
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| Beatriz Alvarez, Universidad de La Republica, Uruguay Reactivty of hydrogen sulfide towards biological oxidants, disulfides and sulfenic acids |
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| Lucia Piacenza, Universidad de La Republica, Uruguay Antioxidant Enzymes of Trypanosoma cruzi as virulent factors for Chagas Disease |
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| Lia Nakao, Universidade Federal do Paraná, Brazil Novel roles of the extracellular flavoprotein quiescin/sulfhydryl oxidase 1 (QSOX1) |
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| Thursday – August 27th, 2015 – 9:00 to 11:00 am – Room: Expocenter IV B | |
| Symposium 22 – Cell Signalling Chair: Jörg Kobarg, Unicamp, Brazil |
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| Rony Seger, Weizmann Institute of Science, Israel The Nuclear Translocation of MAPKs: A Novel Drug Target for Signaling-Related Diseases |
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| Alexandra Newton, University of California (San Diego), USA Reversing the paradigm: protein kinase C as a tumor suppressor |
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| Deborah Schechtman, Universidade de São Paulo, Instituto de Química, Brazil Protein Kinases Read “Braille” |
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| Jörg Kobarg, Universidade de Campinas, Brazil The involvement of members of the human family of Nek kinases in the regulation of the cell cycle, the DNA damage response and beyond |
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| Thursday – August 27th, 2015 – 9:00 to 11:00 am – Room: Expocenter IV C | |
| Symposium 23 – Plant Biochemistry and Molecular Biology Chair: Pio Colepicolo, USP-IQ |
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| Jose Manuel Estevez, Universidad de Buenos Aires, Argentina Ca+2 and ROS master regulators of single plant cell expansion |
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| Eric Lam, Rutgers, The State University of New Jersey, USA Paving the foundation for the novel aquatic agricultural platform of duckweed with genomics |
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| Jesus Aparecido Ferro, Universidade Estadual Paulista Júlio de Mesquita Filho, Brazil Plant–pathogen interactions in citrus canker: An integrated view |
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| Chunlin Long, College of Life and Environmental Sciences, Minzu University of China, China Genetic diversity of buckwheat in different farming and cultural environments in the Himalayas |
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| Thursday – August 27th, 2015 – 9:00 to 11:00 am – Room: Iguaçu I – 5th floor | |
| Symposium 24 – Nanobiotechnology Chair: Henrique Eisi Toma , IQ- Universidade de São Paulo, Brazil |
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| Marin van Heel, Leiden University / Imperial College London Structure and Dynamics of Macromolecular Machines by Single Particle Cryo-EM |
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| Valtencir Zucolotto, IFSC- Universidade de São Paulo, Brazil Advances in Nanomedicine and Nanotoxicology: Novel Nanomaterials for Diagnosis and Therapy |
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| Ehud Gazit, Tel Aviv University, Israel Molecular Self-Assembly of Short Peptides and Metabolites: From Amyloid and Metabolic Diseases to New Biomaterials and Nanotechnology |
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| Henrique Eisi Toma, Instituto de Química, Universidade de São Paulo, Brazil Nanoparticles and Biomolecules: an inspiring partnership |
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| 11:00 to 11:30 – Coffee Break | |
| Thursday – August 27th, 2015 – 11:30 am to 12:30 pm: Expocenter IV | |
| Keynote Lecture 6 Chair: Michael P. Walsh, University of Calgary, Canada |
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| José Onuchic, Rice University, USA From structure to function: the convergence of structure based models and co-evolutionary information |
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| 12:30 to 2 pm – LunchThursday – August 27th, 2015 – 2:00 to 3:00 pm: Expocenter IV | |
| Keynote Lecture 7 Chair: Hugo J. Maccioni, PABMB President and Universidad Nacional de Cordoba, Argentina |
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| Johann Deisenhofer, The University of Texas Southwestern Medical Center and German Academy of Natural Scientists Leopoldina
Structural Biology of Photosynthetic Light Reactions |
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| 3:00 to 3:30 pm – Break Time | |
| Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Expocenter IV A | |
| Symposium 26 – Protein Misfolding Diseases Chair: Sergio T. Ferreira, Universidade Federal do Rio de Janeiro, Brazil |
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| Yuji Goto, University of Osaka, Japan Supersaturation-limited Protein Misfolding Revealed by Ultrasonication |
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Peter Walter, University of California, San Francisco, CA, USA |
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| Harm Kampinga, University of Groningen , The Netherlands Functional specificity of heat shock proteins in dealing with protein aggregation diseases |
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| Sergio T. Ferreira, Universidade Federal do Rio de Janeiro, Brazil Brain inflammation links memory impairment and depressive-like behavior induced by Alzheimer’s ABeta oligomers in rodents |
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| Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Expocenter IV B | |
| Symposium 27 – Redox Signalling Chair: Rafael Radi, Udelar, Uruguay |
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| Francisco Laurindo, Incor-FM- Universidade de São Paulo, Brazil Protein disulfide isomerases in redox signaling and homeostasis: mechanisms and pathophysiological implications |
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| Ohara Augusto, IQ- Universidade de São Paulo, Brazil Protein oxidation: from redox signaling to protein aggregation. |
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| Rafael Radi, Universidad de La Republica, Udelar, Uruguay Advances in the biochemistry of protein tyrosine nitration |
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| Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Expocenter IV C | |
| Symposium 28 – Cell Differenciation Chair: Henning Ulrich, Universidade de São Paulo -IQ, Brazil |
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| Lakshmi Devi, Icahn School of Medicine at Mount Sinai, New York Signaling Networks in Neuronal Differentiation: A Role for G Protein-coupled Receptor Heterodimers in Modulating Signaling |
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Ivan Velasco, UNAM-Universidad Nacional Autonoma del Mexico – IFC, Mexico |
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| James Manley, Columbia University, USA Regulated Processing Of mRNA Precursors During Cell Differentiation |
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Henning Ulrich, Universidade de São Paulo, Brazil |
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| Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Room: Iguaçu I – 5th Floor | |
| Symposium 29 – Portugal-Brazil: Biomembranes and Transporters: New Targets for Old Diseases Chair: Iolanda M. Cuccovia, Universidade de São Paulo -IQ, Brazil |
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| Graça Soveral, Universidade de Lisboa, Portugal Aquaporin channels in membranes: therapeutic targets for chronic diseases |
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| Miguel Castanho, Universidade de Lisboa, Portugal Biomembranes as drug targets for antimicrobial peptides: from vesicles to bacteria |
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| Celso Caruso Neves, Universidade Federal do Rio de Janeiro, Brazil Albumin induces renal disease: role of mTOR pathway |
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| Iolanda M. Cuccovia, Universidade de São Paulo IQ, Brazil Polymer- and Peptide-membrane interactions in model systems |
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| Thursday – August 27th, 2015 – 3:30 pm to 5:30 pm – Room: Iguaçu II – 5th Floor | |
| Symposium 30 – Inflammation Chair: Patrícia Bozza, Fiocruz-IOC, Brazil |
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| Adi Kimchi, The Weizmann Institute, Israel The Protein Interaction Map of Apoptosis and Autophagy: From Basic Science to a Therapeutic Vision |
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| Fernando Cunha, FMRP-Universidade de São Paulo, Brazil Mechanisms involved in the innate immune-dysfunction induced by severe sepsis |
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| Andrew S Weyric, University of Utah
Novel Functions of Platelets in Health and Infectious Disease |
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| Patrícia Bozza, Fiocruz-IOC, Brazil Mechanisms and Functions of Lipid Droplets in Cell Signaling, Inflammation and Cancer |
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| 5:30 to 6:00 pm | Coffee break |
| 6:00 to 8:00 pm |
Poster Session III |
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Friday – August 28th, 2015 |
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| Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Expocenter IV A | |
| Symposium 31 – Infectious diseases Chair: Selma Jerônimo, Universidade Federal do Rio Grande do Norte, Brazil |
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| Bianca Zingales, Instituto de Química, Universidade de São Paulo, Brazil The Molecular Epidemiology of Trypanosoma cruzi and Drug Discovery |
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| Fernando Goldbaum, Inmunología y Microbiología Molecular, Fundación Instituto Leloir, Argentina Development of a Prophylactic Vaccine and Therapeutic Antibodies against Hemolytic Uremic Syndrome using Protein and Antibody Engineering |
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| K. Muniyappa, Indian Institute of Science, India Negative Regulation of Homologous Recombination in Mycobacteria: Insights from Single-molecule Studies |
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| Selma Jerônimo, Universidade Federal do Rio Grande do Norte, Brazil Altered metabolism in tropical diseases: the case of visceral leishmaniasis |
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| Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Expocenter IV B | |
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Symposium 32 – Shedding light on life Chair: Maurício S Baptista, Universidade de São Paulo, Brazil Life is connected to light in several ways. From photosynthesis to the health of humans and being present in countless applications, light have revolutionized our society. In recognition for this and expecting that light will play an increasing role in future technologies, UNESCO decided that 2015 is the INTERNATIONAL YEAR OF LIGHT SBBq prepared this symposium to bring to our society scientific novelties in this field, hoping to foster high-level discussions related with light induced phenomenon |
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| Enrico Gratton, University of California – Irvine, USA Chromatin structure and dynamics |
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| Robert Tabita, Ohio State University, USA Structure, function, and modification of microbial Rubisco From Cultured and uncultured organisms |
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| Etelvino J.H. Bechara,Universidade de São Paulo, Brazil Photochemistry without Light: Mechanisms and Biological Responses |
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| Maurício S Baptista,Universidade de São Paulo, Brazil Exploiting the “double-edged sword” roles of Visible light |
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| Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Expocenter IV C | |
| Symposium 33 – Obesity Chair: Licio Velloso, Universidade de Campinas, Brazil |
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| Deborah Kurrash, University of Calgary, Canada Genetic Programs that Govern Development of Hypothalamic Satiety Centres |
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| Miriam Cnop , Universite Libre de Bruxelles, Belgium A choice of death: beta cell failure in diabetes |
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| Licio Velloso, Universidade de Campinas, BrazilRewiring the damaged obese hypothalamus with polyunsaturated fats | |
| Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Iguaçu I – 5th Floor | |
| Symposium 34 – Cancer Chair: Roger Chammas, Faculdade de Medicina, Universidade de São Paulo, Brazil |
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| Carol Prives, Columbia University, USA The opposing functions of wild-type and mutant forms of p53 |
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| Anamaria Aranha Camargo, Instituto Ludwig, Brazil SIGIRR/TIR8: a new player in the crosstalk between breast tumours and the immune system |
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| M. Iqbal Parker, International Centre for Genetic Engineering and Biotechnology (ICGEB), South Africa Endogenous and Exogenous viral sequences in Oesophageal cancer |
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| Roger Chammas, Faculdade de Medicina, Universidade de São Paulo, Brazil Revisiting the cellular and molecular basis of melanoma chemoresistance: opportunities to innovative combination therapy |
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| Friday – August 28th, 2015 – 9:00 am to 11:00 am – Room: Iguaçu I – 5th Floor> | |
| Symposium 35 – Protein Dynamics and Function Chair: Fabio C.L. de Almeida, Universidade Federal do Rio de Janeiro |
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| Stefano Ciurli, University of Bologna, Italy Structure and dynamics of Jaburetox, an intrinsically disordered polypeptide derived from jack bean urease |
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| Dmitry Korzhnev, University of Connecticut Health Center, USA Interaction Network Of Translesion Synthesis Dna Polymerases |
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Alejandro Buschiazzo, Instituto Pasteur, Uruguay |
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| Fabio C.L. de Almeida, Universidade Federal do Rio de Janeiro, Brazil Dissection of the water cavity of yeast thioredoxin |
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| 11:00 to 11:30 – Coffee Break | |
| Friday – August 28th, 2015 – 11:30 am to 12:30 pm: Room: Expocenter IV | |
| Keynote Lecture Chair: Jerson Lima da Silva, Universidade Federal do Rio de Janeiro, Brazil |
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| Bruce Alberts, University of California (San Francisco), USA The Problems and Challenges in Biomedical Sciences |
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| Friday – August 28th, 2015 – 12:30 to 13:00 pm: Expocenter IV | |
| Closing Ceremony and SBBq Awards | |
| The Announcement of SBBq Awards for best posters presentation and the 19th Prize for Young Talent in Life Sciences | |